On the eastern coast of Sicily, where the realms of Ulysses and Polyphemus intertwine and the fiery slopes of Mount Etna meet the pristine, crystalline waters of the lonian Sea, thrives a unique red seaweed with remarkable properties, known as “U Mauru“ and scientifically as Chondrachantus Teedei.
For generations, local fishermen have valued “U Mauru” as a sustaining indulgence after their fishing trips, attributing to it strength and longevity.
Its robust flavor hints at the sea and iron, reflecting its abundant mineral content iron, calcium, and magnesium-and essential vitamins such as C and B12.
Adapted to thrive in harsh environments, Chondrachantus Teedei is rich in carrageenans, high-molecular weight polysaccharides, and bioactive nutraceuticals like proteins, minerals, fatty acids, and antioxidants.
It is renowned as well for its anti-fungal and antiviral properties, earning it the reputation of a powerhouse and making it highly sought-after for cosmetic formulations.
From pure waters of Ionian Sea
ReCIPEX Technology
Extraction of exosomes from “U Mauru” is a complex and meticulous technology developed and patented by Dermoaroma.
A crisp, structured, with high degree of precision and effectiveness process of extracting exosomes deploying latest technological advancements, while maintaining their integrity and enhancing their properties, involving:
- Breaking seaweed cell walls
- Safegarding membranes
- Release significant amount of exosomes
- Extracting juice
- Centrifugation
- Isolation
- Enhanced Purification
- Harvesting
We call it ReCIPEX – Releasing Cell Internal Proteins, Purifying and Harvesting Algal Exosomes – a sequence of process stages involved in extracting and purifying exosomes from sea algae.
It starts with carefully breaking the seaweed’s cell wall to release a significant amount of exosomes while safeguarding their delicate membranes.
The seaweed juice undergoes multiple centrifugation stages at high speed to isolate and purify a pellet concentrated with exosomes, meeting the highest industry standards.
U Mauru derived exosomes reveal a broad therapeutic potential and establish the future generation of therapies in regenerative medicine and regenerative aesthetics.
Extraction of exosomes from “U Mauru” is a complex and meticulous technology developed and patented by Dermoaroma.
A crisp, structured, with high degree of precision and effectiveness process of extracting exosomes deploying latest technological advancements, while maintaining their integrity and enhancing their properties, involving:
Amplex+ Technology
AMPLEX PLUS is a proprietary technology of isolating and harvesting high yields of Secretomes from organic bovine colostrum, the initial secretion from mammalian glands after parturition, acclaimed as the most abundant source of bioactive elements on the planet.
Secretome is an umbrella term representing a set of proteins expressed by an organism and secreted into the extracellular space, that includes vesicles, protein molecules and other substances as growth factors, chemokines, cytokines, exosomes, adhesion molecule, responsible for provision of nutrients, cell-to-cell communication, detoxification and immune responses.
Sometimes terms Secretomes and Exosomes are used as interchangeable terms, but, in fact, they are not the same.
Secretome is the totality of all messenger substances, including macrovesicles, Growth Factors and Exosomes.
The secretome orchestrates the subtle and complex processes of embryonic development, maintains the function of individual organs, and coordinates organ activity through inter-organ communication (McMahon, chair of the Department of Stem Cell Biology and Regenerative Medicine at USC).
If a human organism was an orchestra, Secretome could have been The Grand Maestro and Growth Factors were the baton, Maestro hold in its hand, and gracefully move through the air to control the pace and the momentum of the symphony.
Secretomes
Growth Factors
Growth Factors is a group of all extracellular regulatory signaling proteins, encompassing cytokines, chemokines and protein hormones (except amine and steroid hormones) that stimulate cell growth, differentiation, survival, inflammation, cell repair and involved in immune responses.
All cytokines are considered as growth factors and currently the terms ‘cytokine’ and ‘growth factor’ are used interchangeably. Interleukins or metabolic (protein) hormones are also classified as growth factors.
Since their discovery by Levi-Montalcini dating back to 1952 to our days scientific world has seen an extraordinary explosion of research on Growth Factors, resulting in a deeper understanding of their function on regulating specific interactions between the cell and the extracellular matrix.
It has been scientifically proven that Growth Factors are capable of triggering cascades of events that lead to tissue regeneration and the formation of new tissues.
Their paramount role in changing cellular behavior, promoting cell proliferation and sprouting new blood vessels placed them on the radars of regenerative aesthetics and regenerative medicine as key components in anti ageing and wound healing therapies.
Exosomes are membrane-bound extracellular vesicles (EVs), produced in the endosomal compartment of most eukaryotic cells, ranging in size from 30 to 150 nanometers.
These spherical shaped extracellular vesicles surrounded by lipid bilayer membrane are recognized as one of the most successful carriers, safely delivering its cargo to the targeted cells and promoting fast absorption.
Their cargoes can include proteins, nucleic acids and metabolites reflecting the nature of donor cell and its physiological state.
A complex of nucleic acids such as DNA, mRNA and noncoding RNA, MicroRNAs (miRs) are the most abundant species of the exosome composition playing important role in multiple biological processes and exosome mediated cellular communication.
Exosomes
D-BIOTECH S.R.L.
Via George Marshall Catlett, 5
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Italy
+39 095 4038460
info@d-biotech.com
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